Short tandem repeat polymorphism evolution in humans
نویسندگان
چکیده
منابع مشابه
Genetic Variation of Informative Short Tandem Repeat (STR) Loci in an Iranian Population
In the present study, genotyping of six short tandem repeat (STR) loci including CSF1PO, D16S539, F13A01, F13B, LPL and HPRTB was performed on genomic DNA from 127 unrelated individuals from the Iranian province of Isfahan. The results indicated that the allele and genotype distributions were in accordance with Hardy-Weinberg expectations. The observed heterozygosity (Ho), expected heterozygosi...
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aim : in this study, genetic polymorphism of two trna-liked short tandem repeat (str)-containing loci, r-r and s-q, was analyzed in order to clarify further the genotypic differences among e. dispar isolates. background : entamoeba dispar is closely related to the human pathogen e. histolytica , the agent of amebic dysentery and amebic liver abscesses. e. dispar is, to some extent, capable of p...
متن کاملStructure and polymorphism of novel X-chromosome short tandem repeat loci in a Chinese Han population.
Recently, 5 novel X-chromosome short tandem repeat (X-STR) loci with high degrees of polymorphism were examined. In this study, we investigated the genetic distribution of these loci in a Chinese Han population. The 5 X-STR loci were successfully examined by polyacrylamide gel electrophoresis in a total of 200 unrelated Shaanxi Han individuals (100 males and 100 females). Hardy-Weinberg equilib...
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BACKGROUND PTPN11, which encodes tyrosine phosphatase Shp2, is a critical gene mediating cellular responses to hormones and cytokines. Loss of Shp2 promotes hepatocellular carcinoma (HCC), suggesting that PTPN11 functions as a tumor suppressor in HCC tumorgenesis. The aim of this study was to evaluate the effects of the short tandem repeat (STR) polymorphism (rs199618935) within 3'UTR of PTPN11...
متن کاملPolymorphism Profile of Nine Short Tandem Repeat Loci in the Han Chinese
Nine short tandem repeat (STR) markers (D3S1358, VWA, FGA, THO1, TPOX, CSFIPO, D5S818, D13S317, and D7S820) and a sex-identification marker (Amelogenin locus) were amplified with multiplex PCR and were genotyped with a four-color fluorescence method in samples from 174 unrelated Han individuals in North China. The allele frequencies, genotype frequencies, heterozygosity, probability of discrimi...
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ژورنال
عنوان ژورنال: European Journal of Human Genetics
سال: 1998
ISSN: 1018-4813,1476-5438
DOI: 10.1038/sj.ejhg.5200151